Benutzer: Gast  Login
Titel:

Embryonic endothelial progenitor cells expressing a broad range of proangiogenic and remodeling factors enhance vascularization and tissue recovery in acute and chronic ischemia.

Dokumenttyp:
Journal Article
Autor(en):
Kupatt, C; Horstkotte, J; Vlastos, GA; Pfosser, A; Lebherz, C; Semisch, M; Thalgott, M; Büttner, K; Browarzyk, C; Mages, J; Hoffmann, R; Deten, A; Lamparter, M; Müller, F; Beck, H; Büning, H; Boekstegers, P; Hatzopoulos, AK
Abstract:
Clonal embryonic endothelial progenitor cells (eEPCs) isolated from embryonic day 7.5 mice home specifically to hypoxic areas in mouse tumor metastases but spare normal organs and do not form carcinomas. Based on these results, we assessed the potential of eEPCs to enhance vascularization and limit organ dysfunction after ischemia in syngenic and xenotypic organisms. The angiogenic potential of eEPCs was evaluated in chronic ischemic rabbit hindlimbs after regional application by retroinfusion....     »
Zeitschriftentitel:
FASEB J
Jahr:
2005
Band / Volume:
19
Heft / Issue:
11
Seitenangaben Beitrag:
1576-8
Sprache:
eng
Volltext / DOI:
doi:10.1096/fj.04-3282fje
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/16009705
Print-ISSN:
0892-6638
TUM Einrichtung:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene
 BibTeX