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Title:

Association of pretherapeutic expression of chemotherapy-related genes with response to neoadjuvant chemotherapy in Barrett carcinoma.

Document type:
Journal Article; Article
Author(s):
Langer, R; Specht, K; Becker, K; Ewald, P; Bekesch, M; Sarbia, M; Busch, R; Feith, M; Stein, HJ; Siewert, JR; Höfler, H
Abstract:
PURPOSE: We analyzed pretherapeutic gene expression patterns of patients with locally advanced adenocarcinomas of the esophagus with regard to response to neoadjuvant chemotherapy. EXPERIMENTAL DESIGN: Pretherapeutic, paraffin-embedded, formalin-fixed endoscopic esophageal tumor biopsies of 38 patients with locally advanced esophageal adenocarcinomas (Barrett adenocarcinoma) were included. All patients underwent two cycles of cisplatin and 5-fluorouracil (5-FU) therapy with or without additional...     »
Journal title abbreviation:
Clin Cancer Res
Year:
2005
Journal volume:
11
Journal issue:
20
Pages contribution:
7462-9
Language:
eng
Fulltext / DOI:
doi:10.1158/1078-0432.CCR-05-0042
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/16243820
Print-ISSN:
1078-0432
TUM Institution:
Chirurgische Klinik und Poliklinik; Institut für Allgemeine Pathologie und Pathologische Anatomie; Institut für Medizinische Statistik und Epidemiologie
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