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Titel:

Expression of p53 and p21 in Primary Glioblastomas.

Dokumenttyp:
Journal Article
Autor(en):
Gross, MW; Kraus, A; Nashwan, K; Mennel, HD; Engenhart-Cabillic, R; Schlegel, J
Abstract:
BACKGROUND AND PURPOSE: : Primary glioblastomas (GBMs) are highly radioresistant, and in contrast to secondary GBMs, they bear wild-type (wt) p53 protein, which is stabilized in a proportion of these tumors. Therefore, it was investigated in vivo whether p53 expression has prognostic value in patients undergoing radiochemotherapy. Additionally, the authors tried to identify, in vitro, subgroups of primary GBM with different susceptibilities to irradiation, on the basis of their p53 and p21 respo...     »
Zeitschriftentitel:
Strahlenther Onkol
Jahr:
2005
Band / Volume:
181
Heft / Issue:
3
Seitenangaben Beitrag:
164-171
Sprache:
eng
Volltext / DOI:
doi:10.1007/s00066-005-1304-z
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/15756520
Print-ISSN:
0179-7158
TUM Einrichtung:
Institut für Allgemeine Pathologie und Pathologische Anatomie
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