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Title:

C-myc gene amplification in different stages of oesophageal squamous cell carcinoma: prognostic value in relation to treatment modality.

Document type:
Journal Article
Author(s):
Bitzer, M; Stahl, M; Arjumand, J; Rees, M; Klump, B; Heep, H; Gabbert, HE; Sarbia, M
Abstract:
BACKGROUND: The proto-oncogene c-myc is known to be involved in the regulation of proliferation, apoptosis and cell differentiation. MATERIALS AND METHODS: Amplification of c-myc was determined by means of differential PCR in 77 surgically treated stage I or II oesophageal squamous cell carcinomas (SCC) as well as in 43 locally advanced SCC (cT3-4 cN0-1 cM0) treated by radiochemotherapy and facultatively by surgery. The findings were correlated to overall survival and to response to radiochemoth...     »
Journal title abbreviation:
Anticancer Res
Year:
2003
Journal volume:
23
Journal issue:
2B
Pages contribution:
1489-93
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/12820414
Print-ISSN:
0250-7005
TUM Institution:
Institut für Allgemeine Pathologie und Pathologische Anatomie
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