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Document type:
Journal Article
Author(s):
Sing, A; Tvardovskaia, N; Rost, D; Kirschning, CJ; Wagner, H; Heesemann, J
Title:
Contribution of toll-like receptors 2 and 4 in an oral Yersinia enterocolitica mouse infection model.
Abstract:
A characteristic of the three human-pathogenic Yersinia spp. (the plague agent Y. pestis and the enteropathogenic Y. pseudotuberculosis and Y. enterocolitica) is the expression of the virulence (V)-antigen (LcrV). LcrV is a released multifunctional protein which is involved in contact-induced secretion of Yersinia antihost proteins and in evasion of the host innate immune response. Recently, we reported that recombinant LcrV signals in a CD14- and TLR2-dependent fashion leading to immunosuppress...     »
Journal title abbreviation:
Int J Med Microbiol
Year:
2003
Journal volume:
293
Journal issue:
5
Pages contribution:
341-8
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/14695062
Print-ISSN:
1438-4221
TUM Institution:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene
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