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Title:

Snail and slug play distinct roles during breast carcinoma progression.

Document type:
Journal Article
Author(s):
Côme, C; Magnino, F; Bibeau, F; De Santa Barbara, P; Becker, KF; Theillet, C; Savagner, P
Abstract:
PURPOSE: Carcinoma progression is linked to a partially dedifferentiated epithelial cell phenotype. As previously suggested, this regulation could involve transcription factors, Snail and Slug, known to promote epithelial-mesenchymal transitions during development. Here, we investigate the role of Snail and Slug in human breast cancer progression. EXPERIMENTAL DESIGN: We analyzed Snail, Slug, and E-cadherin RNA expression levels and protein localization in large numbers of transformed cell lines...     »
Journal title abbreviation:
Clin Cancer Res
Year:
2006
Journal volume:
12
Journal issue:
18
Pages contribution:
5395-402
Language:
eng
Fulltext / DOI:
doi:10.1158/1078-0432.CCR-06-0478
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/17000672
Print-ISSN:
1078-0432
TUM Institution:
Institut für Allgemeine Pathologie und Pathologische Anatomie
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