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Titel:

Mixed T helper cell signatures in chronic rhinosinusitis with and without polyps.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Derycke, Lara; Eyerich, Stefanie; Van Crombruggen, Koen; Pérez-Novo, Claudina; Holtappels, Gabriele; Deruyck, Natalie; Gevaert, Philippe; Bachert, Claus
Abstract:
In chronic rhinosinusitis (CRS) different phenotypes have been reported based on cytokine profile and inflammatory cell patterns. The aim of this study was to characterize the intracytoplasmatic cytokines of T cells infiltrating the inflamed sinonasal mucosa.Infiltrated T cells and tissue homogenates from sinonasal mucosal samples of 7 healthy subjects, 9 patients with CRS without nasal polyp (CRSsNP), 15 with CRS with nasal polyps (CRSwNP) and 5 cystic fibrosis patients (CF-NP) were analyzed fo...     »
Zeitschriftentitel:
PLoS ONE
Jahr:
2014
Band / Volume:
9
Heft / Issue:
6
Seitenangaben Beitrag:
e97581
Sprache:
eng
Volltext / DOI:
doi:10.1371/journal.pone.0097581
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/24911279
Print-ISSN:
1932-6203
TUM Einrichtung:
Molekulare Allergologie (Prof. Schmidt-Weber)
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