Emerging Alternative Functions for the Auxiliary Subunits of the Voltage-Gated Calcium Channels.

Title:: Emerging Alternative Functions for the Auxiliary Subunits of the Voltage-Gated Calcium Channels.
Document type:: Journal Article; Research Support, Non-U.S. Gov't; Review; Article
Author(s):: Hofmann, Franz; Belkacemi, Anouar; Flockerzi, Veit
Abstract:: Voltage gated calcium channels (Cav) are composed of up to five proteins: The ion conducting pore subunit ?1 and the auxiliary subunits ?2, ?, ?, and ?. Recent reports show that Cav?1 and Cav? comprise the calcium channel core complex and that ?, ?2 ? and ? may serve additional roles that are independent of the Cav?1 subunit. This short review will summarize these emerging functions.
Journal title abbreviation:: Curr Mol Pharmacol
Year:: 2015
Journal volume:: 8
Journal issue:: 2
Pages contribution:: 162-8
Language:: eng
Pubmed ID:: http://view.ncbi.nlm.nih.gov/pubmed/25966689
Print-ISSN:: 1874-4672
TUM Institution:: Institut für Pharmakologie und Toxikologie
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