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Title:

Bayesian Cure Rate Modeling of Local Tumor Control: Evaluation in Stereotactic Body Radiation Therapy for Pulmonary Metastases.

Document type:
Journal Article; Multicenter Study; Article
Author(s):
Klement, Rainer J; Allgäuer, Michael; Andratschke, Nicolaus; Blanck, Oliver; Boda-Heggemann, Judit; Dieckmann, Karin; Duma, Marciana; Ernst, Iris; Flentje, Michael; Ganswindt, Ute; Hass, Peter; Henkenberens, Christoph; Imhoff, Detlef; Kahl, Henning K; Krempien, Robert; Lohaus, Fabian; Nestle, Ursula; Nevinny-Stickel, Meinhard; Petersen, Cordula; Schmitt, Vanessa; Semrau, Sabine; Sterzing, Florian; Streblow, Jan; Wendt, Thomas G; Wittig, Andrea; Guckenberger, Matthias
Abstract:
Most radiobiological models for prediction of tumor control probability (TCP) do not account for the fact that many events could remain unobserved because of censoring. We therefore evaluated a set of TCP models that take into account this censoring.We applied 2 fundamental Bayesian cure rate models to a sample of 770 pulmonary metastasis treated with stereotactic body radiation therapy at German, Austrian, and Swiss institutions: (1) the model developed by Chen, Ibrahim and Sinha (the CIS99 mod...     »
Journal title abbreviation:
Int J Radiat Oncol Biol Phys
Year:
2016
Journal volume:
94
Journal issue:
4
Pages contribution:
841-9
Language:
eng
Fulltext / DOI:
doi:10.1016/j.ijrobp.2015.12.004
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/26972657
Print-ISSN:
0360-3016
TUM Institution:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie
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