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Document type:
Journal Article; Research Support, Non-U.S. Gov't 
Author(s):
van Nierop, Gijsbert P; Mautner, Josef; Mitterreiter, Johanna G; Hintzen, Rogier Q; Verjans, Georges M G M 
Title:
Intrathecal CD8 T-cells of multiple sclerosis patients recognize lytic Epstein-Barr virus proteins. 
Abstract:
The association between Epstein-Barr virus (EBV) and multiple sclerosis (MS) may involve intrathecal EBV-specific T-cell responses targeting the virus or indirectly, autoantigens.Compare the prevalence and fine-specificity of EBV-specific T-cells in the cerebrospinal fluid (CSF) of patients with MS (n = 12), clinically-isolated syndrome (CIS) (n = 17) and other neurological diseases (OND) (n = 13).Intrathecal EBV-specific T-cell reactivity was assayed using CSF-derived T-cell lines (CSF-TCL) and...    »
 
Journal title abbreviation:
Mult Scler 
Year:
2016 
Journal volume:
22 
Journal issue:
Pages contribution:
279-91 
Language:
eng 
Fulltext / DOI:
Print-ISSN:
1352-4585 
TUM Institution:
Klinik und Poliklinik für Kinderheilkunde und Jugendmedizin