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Title:

Dysregulation of proinflammatory versus anti-inflammatory human TH17 cell functionalities in the autoinflammatory Schnitzler syndrome.

Document type:
Journal Article
Author(s):
Noster, Rebecca; de Koning, Heleen D; Maier, Elisabeth; Prelog, Martina; Lainka, Elke; Zielinski, Christina E
Abstract:
TH17 cells have so far been considered to be crucial mediators of autoimmune inflammation. Two distinct types of TH17 cells have been described recently, which differed in their polarization requirement for IL-1? and in their cytokine repertoire. Whether these distinct TH17 phenotypes translate into distinct TH17 cell functions with implications for human health or disease has not been addressed yet.We hypothesized the existence of proinflammatory and anti-inflammatory human TH17 cell functions...     »
Journal title abbreviation:
J Allergy Clin Immunol
Year:
2016
Journal volume:
138
Journal issue:
4
Pages contribution:
1161-1169.e6
Language:
eng
Fulltext / DOI:
doi:10.1016/j.jaci.2015.12.1338
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/27040374
Print-ISSN:
0091-6749
TUM Institution:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene
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