User: Guest  Login
Title:

TIL 2.0: More effective and predictive T-cell products by enrichment for defined antigen specificities.

Document type:
Journal Article
Author(s):
Schober, Kilian; Busch, Dirk H
Abstract:
Adoptive transfer of in vitro-expanded T cells derived from tumor-infiltrating lymphocytes (TILs) in melanoma patients started the era of tumor immunotherapy three decades ago. The approach has demonstrated remarkable clinical responses in several studies since. Reinfusion of TIL-derived T cells represents a highly personalized form of immunotherapy, taking into account the enormous interindividual tumor heterogeneity. However, despite its successes, TIL therapy does not lead to objective clinic...     »
Journal title abbreviation:
Eur J Immunol
Year:
2016
Journal volume:
46
Journal issue:
6
Pages contribution:
1335-9
Language:
eng
Fulltext / DOI:
doi:10.1002/eji.201646436
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/27280482
Print-ISSN:
0014-2980
TUM Institution:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene
 BibTeX