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Title:

Murine cytomegalovirus (CMV) infection via the intranasal route offers a robust model of immunity upon mucosal CMV infection.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Oduro, Jennifer D; Redeker, Anke; Lemmermann, Niels A W; Ebermann, Linda; Marandu, Thomas F; Dekhtiarenko, Iryna; Holzki, Julia K; Busch, Dirk H; Arens, Ramon; ?i?in-?ain, Luka
Abstract:
Cytomegalovirus (CMV) is a ubiquitous virus, causing the most common congenital infection in humans, yet a vaccine against this virus is not available. Experimental studies of immunity against CMV in animal models of infection, such as the infection of mice with mouse CMV (MCMV), have relied mainly on parenteral infection protocols, although the virus naturally transmits by mucosal routes via body fluids. To characterize the biology of infections by mucosal routes, we compared the kinetics of vi...     »
Journal title abbreviation:
J Gen Virol
Year:
2016
Journal volume:
97
Journal issue:
1
Pages contribution:
185-95
Language:
eng
Fulltext / DOI:
doi:10.1099/jgv.0.000339
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/26555192
Print-ISSN:
0022-1317
TUM Institution:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene
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