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Title:

Adipose Tissue Lipolysis Promotes Exercise-induced Cardiac Hypertrophy Involving the Lipokine C16:1n7-Palmitoleate.

Document type:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Article
Author(s):
Foryst-Ludwig, Anna; Kreissl, Michael C; Benz, Verena; Brix, Sarah; Smeir, Elia; Ban, Zsofia; Januszewicz, El?bieta; Salatzki, Janek; Grune, Jana; Schwanstecher, Anne-Kathrin; Blumrich, Annelie; Schirbel, Andreas; Klopfleisch, Robert; Rothe, Michael; Blume, Katharina; Halle, Martin; Wolfarth, Bernd; Kershaw, Erin E; Kintscher, Ulrich
Abstract:
Endurance exercise training induces substantial adaptive cardiac modifications such as left ventricular hypertrophy (LVH). Simultaneously to the development of LVH, adipose tissue (AT) lipolysis becomes elevated upon endurance training to cope with enhanced energy demands. In this study, we investigated the impact of adipose tissue lipolysis on the development of exercise-induced cardiac hypertrophy. Mice deficient for adipose triglyceride lipase (Atgl) in AT (atATGL-KO) were challenged with chr...     »
Journal title abbreviation:
J Biol Chem
Year:
2015
Journal volume:
290
Journal issue:
39
Pages contribution:
23603-15
Language:
eng
Fulltext / DOI:
doi:10.1074/jbc.M115.645341
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/26260790
Print-ISSN:
0021-9258
TUM Institution:
Poliklinik für Präventive und Rehabilitative Sportmedizin
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