Benutzer: Gast  Login
Weniger Felder
Einfache Suche
Titel:

Prognostic relevance of miRNA-155 methylation in anaplastic glioma.

Dokumenttyp:
Journal Article
Autor(en):
Schliesser, Maximilian Georg; Claus, Rainer; Hielscher, Thomas; Grimm, Christiane; Weichenhan, Dieter; Blaes, Jonas; Wiestler, Benedikt; Hau, Peter; Schramm, Johannes; Sahm, Felix; Weiß, Elisa K; Weiler, Markus; Baer, Constance; Schmidt-Graf, Friederike; Schackert, Gabriele; Westphal, Manfred; Hertenstein, Anne; Roth, Patrick; Galldiks, Norbert; Hartmann, Christian; Pietsch, Torsten; Felsberg, Joerg; Reifenberger, Guido; Sabel, Michael Christoph; Winkler, Frank; von Deimling, Andreas; Meisner, C...     »
Abstract:
The outcome of patients with anaplastic gliomas varies considerably depending on single molecular markers, such as mutations of the isocitrate dehydrogenase (IDH) genes, as well as molecular classifications based on epigenetic or genetic profiles. Remarkably, 98% of the RNA within a cell is not translated into proteins. Of those, especially microRNAs (miRNAs) have been shown not only to have a major influence on physiologic processes but also to be deregulated and prognostic in malignancies.To f...     »
Zeitschriftentitel:
Oncotarget
Jahr:
2016
Band / Volume:
7
Heft / Issue:
50
Seitenangaben Beitrag:
82028-82045
Sprache:
eng
Volltext / DOI:
doi:10.18632/oncotarget.13452
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/27880937
TUM Einrichtung:
Fachgebiet Neuroradiologie (Prof. Zimmer); Neurologische Klinik und Poliklinik
 BibTeX