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Titel:

Near-Infrared Photoacoustic Imaging Probe Responsive to Calcium.

Dokumenttyp:
Journal Article; Article
Autor(en):
Mishra, Anurag; Jiang, Yuanyuan; Roberts, Sheryl; Ntziachristos, Vasilis; Westmeyer, Gil G
Abstract:
Photoacoustic imaging (PAI) is an attractive imaging modality that can volumetrically map the distribution of photoabsorbing molecules with deeper tissue penetration than multiphoton microscopy. To enable dynamic sensing of divalent cations via PAI, we have engineered a new reversible near-infrared probe that is more sensitive to calcium as compared to other biologically relevant cations. The metallochromic compound showed a strong reduction of its peak absorbance at 765 nm upon addition of calc...     »
Zeitschriftentitel:
Anal Chem
Jahr:
2016
Band / Volume:
88
Heft / Issue:
22
Seitenangaben Beitrag:
10785-10789
Sprache:
eng
Volltext / DOI:
doi:10.1021/acs.analchem.6b03039
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/27779396
Print-ISSN:
0003-2700
TUM Einrichtung:
Klinik und Poliklinik für Nuklearmedizin; Lehrstuhl für Biologische Bildgebung - Zusammenarbeit mit dem Helmholtz-Zentrum München (Prof. Ntziachristos)
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