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Title:

Near-Infrared Photoacoustic Imaging Probe Responsive to Calcium.

Document type:
Journal Article; Article
Author(s):
Mishra, Anurag; Jiang, Yuanyuan; Roberts, Sheryl; Ntziachristos, Vasilis; Westmeyer, Gil G
Abstract:
Photoacoustic imaging (PAI) is an attractive imaging modality that can volumetrically map the distribution of photoabsorbing molecules with deeper tissue penetration than multiphoton microscopy. To enable dynamic sensing of divalent cations via PAI, we have engineered a new reversible near-infrared probe that is more sensitive to calcium as compared to other biologically relevant cations. The metallochromic compound showed a strong reduction of its peak absorbance at 765 nm upon addition of calc...     »
Journal title abbreviation:
Anal Chem
Year:
2016
Journal volume:
88
Journal issue:
22
Pages contribution:
10785-10789
Language:
eng
Fulltext / DOI:
doi:10.1021/acs.analchem.6b03039
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/27779396
Print-ISSN:
0003-2700
TUM Institution:
Klinik und Poliklinik für Nuklearmedizin; Lehrstuhl für Biologische Bildgebung - Zusammenarbeit mit dem Helmholtz-Zentrum München (Prof. Ntziachristos)
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