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Title:

Periostin and tumor-stroma interactions in non-small cell lung cancer.

Document type:
Journal Article
Author(s):
Nitsche, Ulrich; Stangel, Daniela; Pan, Zheng; Schlitter, Anna Melissa; Esposito, Irene; Regel, Ivonne; Raulefs, Susanne; Friess, Helmut; Kleeff, Jörg; Erkan, Mert
Abstract:
Non-small cell lung cancer (NSCLC) is one of the leading causes of cancer-associated mortality globally. Interactions of the cancer cells with the tumor microenvironment are essential carcinogenic features for the majority of solid tumors, such as pancreatic cancer. The present study investigated the role of stromal activation in NSCLC and analyzed the surgical specimens of 93 patients by immunohistochemistry with regard to periostin (an extracellular matrix protein), ?-smooth muscle actin (?-SM...     »
Journal title abbreviation:
Oncol Lett
Year:
2016
Journal volume:
12
Journal issue:
5
Pages contribution:
3804-3810
Language:
eng
Fulltext / DOI:
doi:10.3892/ol.2016.5132
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/27895734
Print-ISSN:
1792-1074
TUM Institution:
Chirurgische Klinik und Poliklinik; Institut für Allgemeine Pathologie und Pathologische Anatomie
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