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Titel:

Impact of NKT Cells and LFA-1 on Liver Regeneration under Subseptic Conditions.

Dokumenttyp:
Journal Article; Article
Autor(en):
Jörger, Ann-Kathrin; Liu, Lei; Fehlner, Karin; Weisser, Tanja; Cheng, Zhangjun; Lu, Miao; Höchst, Bastian; Bolzer, Andreas; Wang, Baocai; Hartmann, Daniel; Assfalg, Volker; Sunami, Yoshiaki; Schlitter, Anna Melissa; Friess, Helmut; Hüser, Norbert; Laschinger, Melanie
Abstract:
Activation of the immune system in terms of subseptic conditions during liver regeneration is of paramount clinical importance. However, little is known about molecular mechanisms and their mediators that control hepatocyte proliferation. We sought to determine the functional role of immune cells, especially NKT cells, in response to partial hepatectomy (PH), and to uncover the impact of the integrin lymphocyte function-associated antigen-1 (LFA-1) on liver regeneration in a subseptic setting.Wi...     »
Zeitschriftentitel:
PLoS ONE
Jahr:
2016
Band / Volume:
11
Heft / Issue:
12
Seitenangaben Beitrag:
e0168001
Sprache:
eng
Volltext / DOI:
doi:10.1371/journal.pone.0168001
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/27977747
Print-ISSN:
1932-6203
TUM Einrichtung:
Chirurgische Klinik und Poliklinik; Institut für Allgemeine Pathologie und Pathologische Anatomie; Roman Herzog Comprehensive Cancer Center
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