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Document type:
Journal Article; Review; Review 
Author(s):
Reichert, Maximilian; Blume, Karin; Kleger, Alexander; Hartmann, Daniel; von Figura, Guido 
Title:
Developmental Pathways Direct Pancreatic Cancer Initiation from Its Cellular Origin. 
Abstract:
Pancreatic ductal adenocarcinoma (PDA) is characterized by an extremely poor prognosis, since it is usually diagnosed at advanced stages. In order to employ tools for early detection, a better understanding of the early stages of PDA development from its main precursors, pancreatic intraepithelial neoplasia (PanIN), and intraductal papillary mucinous neoplasm (IPMN) is needed. Recent studies on murine PDA models have identified a different exocrine origin for PanINs and IPMNs. In both processes,...    »
 
Journal title abbreviation:
Stem Cells Int 
Year:
2016 
Journal volume:
2016 
Pages contribution:
9298535 
Language:
eng 
Fulltext / DOI:
Print-ISSN:
1687-966X 
TUM Institution:
Chirurgische Klinik und Poliklinik; II. Medizinische Klinik und Poliklinik (Gastroenterologie)