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Title:

Identification of novel immune phenotypes for allergic and nonallergic childhood asthma.

Document type:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Raedler, Diana; Ballenberger, Nikolaus; Klucker, Elisabeth; Bock, Andreas; Otto, Ragna; Prazeres da Costa, Olivia; Holst, Otto; Illig, Thomas; Buch, Thorsten; von Mutius, Erika; Schaub, Bianca
Abstract:
Childhood asthma is classified into allergic asthma (AA) and nonallergic asthma (NA), yet both are treated identically, with only partial success.We sought to identify novel immune phenotypes for childhood AA and NA.The Clinical Asthma Research Association cohort study includes 275 steroid-naive 4- to 15-year-old German children (healthy control subjects [HCs], patients with AA, and patients with NA). In PBMCs both quantitative and functional analysis of regulatory T (Treg) and TH17 cells (flow...     »
Journal title abbreviation:
J Allergy Clin Immunol
Year:
2015
Journal volume:
135
Journal issue:
1
Pages contribution:
81-91
Language:
eng
Fulltext / DOI:
doi:10.1016/j.jaci.2014.07.046
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/25226851
Print-ISSN:
0091-6749
TUM Institution:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene
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