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Titel:

The influence of stromal cells on the pigmentation of tissue-engineered dermo-epidermal skin grafts.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Biedermann, Thomas; Böttcher-Haberzeth, Sophie; Klar, Agnieszka S; Widmer, Daniel S; Pontiggia, Luca; Weber, Andreas D; Weber, Daniel M; Schiestl, Clemens; Meuli, Martin; Reichmann, Ernst
Abstract:
It has been shown in vitro that melanocyte proliferation and function in palmoplantar skin is regulated by mesenchymal factors derived from fibroblasts. In this study, we investigated in vivo the influence of mesenchymal-epithelial interactions in human tissue-engineered skin substitutes reconstructed from palmar- and nonpalmoplantar-derived fibroblasts. Tissue-engineered dermo-epidermal analogs based on collagen type I hydrogels were populated with either human palmar or nonpalmoplantar fibrobl...     »
Zeitschriftentitel:
Tissue Eng Part A
Jahr:
2015
Band / Volume:
21
Heft / Issue:
5-6
Seitenangaben Beitrag:
960-9
Sprache:
eng
Volltext / DOI:
doi:10.1089/ten.TEA.2014.0327
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/25300246
Print-ISSN:
1937-3341
TUM Einrichtung:
Klinik und Poliklinik für Dermatologie und Allergologie
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