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Titel:

Premetastatic niche formation in the liver: emerging mechanisms and mouse models.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Krüger, Achim
Abstract:
The liver is recognized as the target organ of metastases of almost all prominent malignancies. Its unique biology renders this organ particularly susceptible to circulating disseminated tumour cells (DTCs), and it can be assumed that very early metastasis occurs in the liver. The premetastatic niche concept may explain very early metastasis, as it defines priming of a future target organ of metastasis by factors that may already be secreted from premalignant lesions. This review shows that comp...     »
Zeitschriftentitel:
J Mol Med
Jahr:
2015
Band / Volume:
93
Heft / Issue:
11
Seitenangaben Beitrag:
1193-201
Sprache:
eng
Volltext / DOI:
doi:10.1007/s00109-015-1342-7
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/26400831
Print-ISSN:
0946-2716
TUM Einrichtung:
Institut für Experimentelle Onkologie und Therapieforschung
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