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Title:

Manipulation of T cell function and conditional gene targeting in T cells.

Document type:
Journal Article
Author(s):
Sledzi?ska, Anna; Fairbairn, Lynsey; Buch, Thorsten
Abstract:
Cre-Lox recombination is known as a site-specific recombinase technology, and is widely used to carry out modification at specific sites in the DNA of cells. The system consists of an enzyme, Cre recombinase, that recombines a pair of short target sequences, the lox sites. The Cre-Lox system can be used to activate or repress a gene depending on the placement of the lox sites. Placing the Cre recombinase under the control of a cell-specific promoter allows expression only in specific cells or ce...     »
Journal title abbreviation:
Methods Mol Biol
Year:
2014
Journal volume:
1193
Pages contribution:
153-69
Language:
eng
Fulltext / DOI:
doi:10.1007/978-1-4939-1212-4_15
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/25151005
Print-ISSN:
1064-3745
TUM Institution:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene
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