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Titel:

Tetra-acetylajugasterone a new constituent of Vitex cienkowskii with vasorelaxant activity.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Dongmo, Alain Bertrand; Nkeng-Efouet, Pepin Alango; Devkota, Krishna Prasad; Wegener, Jörg W; Sewald, Norbert; Wagner, Hildebert; Vierling, Wolfgang
Abstract:
Tetra-acetylajugasterone C (TAAC) was found to be one of the naturally occurring compounds of the Cameroonian medicinal plant Vitex cienkowskii which is responsible for a vasorelaxant activity of an extract of this plant. The evaluation of the underlying mechanisms for the relaxing effect of TAAC was determined using aortic rings of rats and mice. TAAC produced a concentration-dependent relaxation in rat artery rings pre-contracted with 1?M noradrenaline (IC50: 8.40?M) or 60mM KCl (IC50: 36.30?M...     »
Zeitschriftentitel:
Phytomedicine
Jahr:
2014
Band / Volume:
21
Heft / Issue:
6
Seitenangaben Beitrag:
787-92
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.phymed.2014.02.009
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/24680617
Print-ISSN:
0944-7113
TUM Einrichtung:
Institut für Pharmakologie und Toxikologie
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