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Titel:

Cell-specific blood-brain barrier regulation in health and disease: a focus on hypoxia.

Dokumenttyp:
journal article
Autor(en):
Engelhardt, S, S; Patkar, S, S; Ogunshola, O O, OO
Abstract:
The blood-brain barrier (BBB) is a complex vascular structure consisting of microvascular endothelial cells that line the vessel wall, astrocyte end-feet, pericytes, as well as the basal lamina. BBB cells act in concert to maintain the characteristic impermeable and low paracellular flux of the brain vascular network, thus ensuring a homeostatic neuronal environment. Alterations in BBB stability that occur during injury have dire consequences on disease progression and it is clear that BBB cell-...     »
Zeitschriftentitel:
Br J Pharmacol
Jahr:
2014
Band / Volume:
171
Heft / Issue:
5
Seitenangaben Beitrag:
1210-30
Sprache:
eng
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/24641185
Print-ISSN:
0007-1188
TUM Einrichtung:
Institut für Pharmakologie und Toxikologie
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