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Titel:

L-type CaV1.2 calcium channels: from in vitro findings to in vivo function.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Review
Autor(en):
Hofmann, Franz; Flockerzi, Veit; Kahl, Sabine; Wegener, Jörg W
Abstract:
The L-type Cav1.2 calcium channel is present throughout the animal kingdom and is essential for some aspects of CNS function, cardiac and smooth muscle contractility, neuroendocrine regulation, and multiple other processes. The L-type CaV1.2 channel is built by up to four subunits; all subunits exist in various splice variants that potentially affect the biophysical and biological functions of the channel. Many of the CaV1.2 channel properties have been analyzed in heterologous expression syste...     »
Zeitschriftentitel:
Physiol Rev
Jahr:
2014
Band / Volume:
94
Heft / Issue:
1
Seitenangaben Beitrag:
303-26
Sprache:
eng
Volltext / DOI:
doi:10.1152/physrev.00016.2013
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/24382889
Print-ISSN:
0031-9333
TUM Einrichtung:
Institut für Pharmakologie und Toxikologie
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