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Title:

Ischemic tissue injury in the dorsal skinfold chamber of the mouse: a skin flap model to investigate acute persistent ischemia.

Document type:
Journal Article
Author(s):
Harder, Yves; Schmauss, Daniel; Wettstein, Reto; Egaña, Jose T; Weiss, Fabian; Weinzierl, Andrea; Schuldt, Anna; Machens, Hans-Günther; Menger, Michael D; Rezaeian, Farid
Abstract:
Despite profound expertise and advanced surgical techniques, ischemia-induced complications ranging from wound breakdown to extensive tissue necrosis are still occurring, particularly in reconstructive flap surgery. Multiple experimental flap models have been developed to analyze underlying causes and mechanisms and to investigate treatment strategies to prevent ischemic complications. The limiting factor of most models is the lacking possibility to directly and repetitively visualize microvascu...     »
Journal title abbreviation:
J Vis Exp
Year:
2014
Journal issue:
93
Pages contribution:
e51900
Language:
eng
Fulltext / DOI:
doi:10.3791/51900
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/25489743
Print-ISSN:
1940-087X
TUM Institution:
Lehrstuhl für Plastische Chirurgie und Handchirurgie (Prof. Machens)
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