Simons, Mikael;Levin, Johannes;Dichgans, Martin
Tipping points in neurodegeneration.
Neuron
2023
111
19
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Finze, Anika;Biechele, Gloria;Rauchmann, Boris-Stephan;Franzmeier, Nicolai;Palleis, Carla;Katzdobler, Sabrina;Weidinger, Endy;Guersel, Selim;Schuster, Sebastian;Harris, Stefanie;Schmitt, Julia;Beyer, Leonie;Gnörich, Johannes;Lindner, Simon;Albert, Nathalie L;Wetzel, Christian H;Rupprecht, Rainer;Rominger, Axel;Danek, Adrian;Burow, Lena;Kurz, Carolin;Tato, Maia;Utecht, Julia;Papazov, Boris;Zaganjori, Mirlind;Trappmann, Lena-Katharina;Goldhardt, Oliver;Grimmer, Timo;Haeckert, Jan;Janowitz, Daniel;Buerger, Katharina;Keeser, Daniel;Stoecklein, Sophia;Dietrich, Olaf;Morenas-Rodriguez, Estrella;Barthel, Henryk;Sabri, Osama;Bartenstein, Peter;Simons, Mikael;Haass, Christian;Höglinger, Günter U;Levin, Johannes;Perneczky, Robert;Brendel, Matthias
Individual regional associations between Aβ-, tau- and neurodegeneration (ATN) with microglial activation in patients with primary and secondary tauopathies.
Mol Psychiatry
2023
28
10
4438-4450

Dawkins, Edgar;Derks, Rico J E;Schifferer, Martina;Trambauer, Johannes;Winkler, Edith;Simons, Mikael;Paquet, Dominik;Giera, Martin;Kamp, Frits;Steiner, Harald
Membrane lipid remodeling modulates γ-secretase processivity.
J Biol Chem
2023
299
4

Groh, Janos;Abdelwahab, Tassnim;Kattimani, Yogita;Hörner, Michaela;Loserth, Silke;Gudi, Viktoria;Adalbert, Robert;Imdahl, Fabian;Saliba, Antoine-Emmanuel;Coleman, Michael;Stangel, Martin;Simons, Mikael;Martini, Rudolf
Microglia-mediated demyelination protects against CD8+ T cell-driven axon degeneration in mice carrying PLP defects.
Nat Commun
2023
14
1

Djannatian, Minou;Radha, Swathi;Weikert, Ulrich;Safaiyan, Shima;Wrede, Christoph;Deichsel, Cassandra;Kislinger, Georg;Rhomberg, Agata;Ruhwedel, Torben;Campbell, Douglas S;van Ham, Tjakko;Schmid, Bettina;Hegermann, Jan;Möbius, Wiebke;Schifferer, Martina;Simons, Mikael
Myelination generates aberrant ultrastructure that is resolved by microglia.
J Cell Biol
2023
222
3

Androvic, Peter;Schifferer, Martina;Perez Anderson, Katrin;Cantuti-Castelvetri, Ludovico;Jiang, Hanyi;Ji, Hao;Liu, Lu;Gouna, Garyfallia;Berghoff, Stefan A;Besson-Girard, Simon;Knoferle, Johanna;Simons, Mikael;Gokce, Ozgun
Spatial Transcriptomics-correlated Electron Microscopy maps transcriptional and ultrastructural responses to brain injury.
Nat Commun
2023
14
1

Depp, Constanze;Sun, Ting;Sasmita, Andrew Octavian;Spieth, Lena;Berghoff, Stefan A;Nazarenko, Taisiia;Overhoff, Katharina;Steixner-Kumar, Agnes A;Subramanian, Swati;Arinrad, Sahab;Ruhwedel, Torben;Möbius, Wiebke;Göbbels, Sandra;Saher, Gesine;Werner, Hauke B;Damkou, Alkmini;Zampar, Silvia;Wirths, Oliver;Thalmann, Maik;Simons, Mikael;Saito, Takashi;Saido, Takaomi;Krueger-Burg, Dilja;Kawaguchi, Riki;Willem, Michael;Haass, Christian;Geschwind, Daniel;Ehrenreich, Hannelore;Stassart, Ruth;Nave, Klaus-Armin
Myelin dysfunction drives amyloid-β deposition in models of Alzheimer's disease.
Nature
2023
618
7964
349-357

Biechele, Gloria;Finze, Anika;Rauchmann, Boris-Stephan;Franzmeier, Nikolai;Palleis, Carla;Katzdobler, Sabrina;Endy, Weidinger;Guersel, Selim;Schuster, Sebastian;Harris, Stefanie;Beyer, Leonie;Gnoerich, Johannes;Lindner, Simon;Albert, Nathalie;Wetzel, Christian;Rupprecht, Rainer;Rominger, Axel;Danek, Adrian;Burow, Lena;Kurz, Carolin;Tato, Maia;Utecht, Julia;Papazov, Boris;Zaganjori, Mirlind;Trappmann, Lena-Katharina;Grimmer, Timo;Goldhardt, Oliver;Haeckert, Jan;Janowitz, Daniel;Buerger, Katharina;Keeser, Daniel;Stoecklein, Sophia;Dietrich, Olaf;Morenas-Rodriguez, Estrell;Barthel, Henryk;Sabri, Osama;Bartenstein, Peter;Simons, Mikael;Haass, Christian;Hoeglinger, Guenther;Levin, Johannes;Perneczky, Robert;Brendel, Matthias
Individual regional associations between Aß, tau- and neurodegeneration (ATN) with microglial activation in patients with primary and secondary tauopathies
J Nucl Med
2023
64 Suppl 1

Bosch-Queralt, Mar;Cantuti-Castelvetri, Ludovico;Damkou, Alkmini;Schifferer, Martina;Schlepckow, Kai;Alexopoulos, Ioannis;Lütjohann, Dieter;Klose, Christian;Vaculčiaková, Lenka;Masuda, Takahiro;Prinz, Marco;Monroe, Kathryn M;Di Paolo, Gilbert;Lewcock, Joseph W;Haass, Christian;Simons, Mikael
Author Correction: Diet-dependent regulation of TGFβ impairs reparative innate immune responses after demyelination.
Nat Metab
2023
5
3

Ancau, Mihai;Tanti, Goutam;Butenschoen, Vicki;Gempt, Jens;Yakushev, Igor;Nekolla, Stephan;Muehlau, Mark;Scheunemann, Christian;Heininger, Sebastian;Loewe, Benjamin;Loewe, Erik;Baer, Silke;Fischer, Johannes;Reiser, Judith;Liesche-Starnecker, Friederike;Schlegel, Juergen;Matiasek, Kaspar;Fetting, Martina;Kirschke, Jan;Misgeld, Thomas;Lueth, Tim;Hemmer, Bernhard
Multimodally trackable and reversible cerebral demyelination by electromagnetic-guided injection into the pig brain
Mult Scler
2023
29 Suppl 3
214-215