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Title:

Subcortical cytoskeleton periodicity throughout the nervous system.

Document type:
Journal Article; Research Support, Non-U.S. Gov't; Article
Author(s):
D'Este, Elisa; Kamin, Dirk; Velte, Caroline; Göttfert, Fabian; Simons, Mikael; Hell, Stefan W
Abstract:
Superresolution fluorescence microscopy recently revealed a ~190 nm periodic cytoskeleton lattice consisting of actin, spectrin, and other proteins underneath the membrane of cultured hippocampal neurons. Whether the periodic cytoskeleton lattice is a structural feature of all neurons and how it is modified when axons are ensheathed by myelin forming glial cells is not known. Here, STED nanoscopy is used to demonstrate that this structure is a commonplace of virtually all neuron types in vitro....     »
Journal title abbreviation:
Sci Rep
Year:
2016
Journal volume:
6
Pages contribution:
22741
Language:
eng
Fulltext / DOI:
doi:10.1038/srep22741
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/26947559
Print-ISSN:
2045-2322
TUM Institution:
Lehrstuhl für Zellbiologie des Nervensystems (Prof. Misgeld)
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