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Title:

Tissue-specific tumorigenesis: context matters.

Document type:
Journal Article; Review; Review
Author(s):
Schneider, Günter; Schmidt-Supprian, Marc; Rad, Roland; Saur, Dieter
Abstract:
How can we treat cancer more effectively? Traditionally, tumours from the same anatomical site are treated as one tumour entity. This concept has been challenged by recent breakthroughs in cancer genomics and translational research that have enabled molecular tumour profiling. The identification and validation of cancer drivers that are shared between different tumour types, spurred the new paradigm to target driver pathways across anatomical sites by off-label drug use, or within so-called bask...     »
Journal title abbreviation:
Nat Rev Cancer
Year:
2017
Journal volume:
17
Journal issue:
4
Pages contribution:
239-253
Language:
eng
Fulltext / DOI:
doi:10.1038/nrc.2017.5
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/28256574
Print-ISSN:
1474-175X
TUM Institution:
II. Medizinische Klinik und Poliklinik (Gastroenterologie); III. Medizinische Klinik und Poliklinik (Hämatologie / Onkologie); Professur für Translationale gastroenterologische Onkologie (Prof. Rad)
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