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Title:

Functional optoacoustic neuro-tomography of calcium fluxes in adult zebrafish brain in vivo.

Document type:
Journal Article
Author(s):
Deán-Ben, X Luís; Gottschalk, Sven; Sela, Gali; Shoham, Shy; Razansky, Daniel
Abstract:
Genetically-encoded calcium indicators (GECIs) have revolutionized neuroimaging by enabling mapping of the activity of entire neuronal populations in vivo. Visualization of these powerful activity sensors has to date been limited to depth-restricted microscopic studies due to intense light scattering in the brain. We demonstrate, for the first time, in vivo real-time volumetric optoacoustic monitoring of calcium transients in adult transgenic zebrafish expressing the GCaMP5G calcium indicator. F...     »
Journal title abbreviation:
Opt Lett
Year:
2017
Journal volume:
42
Journal issue:
5
Pages contribution:
959-962
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/28248341
Print-ISSN:
0146-9592
TUM Institution:
Lehrstuhl für Biologische Bildgebung - Zusammenarbeit mit dem Helmholtz-Zentrum München (Prof. Ntziachristos)
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