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Titel:

Intravital optoacoustic and ultrasound bio-microscopy reveal radiation-inhibited skull angiogenesis.

Dokumenttyp:
Article; Journal Article
Autor(en):
Estrada, Héctor; Rebling, Johannes; Sievert, Wolfgang; Hladik, Daniela; Hofmann, Urs; Gottschalk, Sven; Tapio, Soile; Multhoff, Gabriele; Razansky, Daniel
Abstract:
Angiogenesis is critical in bone development and growth. Dense, large-scale, and multi-layered vascular networks formed by thin-walled sinusoidal vessels perfuse the plate bones and play an important role in bone repair. Yet, the intricate functional morphology of skull microvasculature remains poorly understood as it is difficult to visualize using existing intravital microscopy techniques. Here we introduced an intravital, fully-transcranial imaging approach based on hybrid optoacoustic and ul...     »
Zeitschriftentitel:
Bone
Zeitschriftentitel:
Bone
Jahr:
2020
Band / Volume:
133
Volltext / DOI:
doi:10.1016/j.bone.2020.115251
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/31978616
WWW:
https://www.sciencedirect.com/science/article/abs/pii/S8756328220300314
Print-ISSN:
8756-3282
TUM Einrichtung:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie (Prof. Combs); Lehrstuhl für Biologische Bildgebung - Zusammenarbeit mit dem Helmholtz-Zentrum München (Prof. Ntziachristos)
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