LINE(1)s of Evidence in HBV-Driven Liver Cancer.

Title:: LINE(1)s of Evidence in HBV-Driven Liver Cancer.
Document type:: journal article
Author(s):: Heikenwalder, Mathias, M; Protzer, Ulrike, U
Abstract:: Hepatitis B virus (HBV) integration in hepatocellular carcinoma (HCC) is a poorly understood event. In a recent Cancer Cell paper, Lau et al. (2014) describe a HBV-human fusion transcript (HBx-LINE1) that functions as a lncRNA, influences the epithelial-mesenchymal transition, and correlates with reduced patient survival and tumor formation in mice.
Journal title abbreviation:: Cell Host Microbe
Year:: 2014
Journal volume:: 15
Journal issue:: 3
Pages contribution:: 249-50
Language:: eng
Pubmed ID:: http://view.ncbi.nlm.nih.gov/pubmed/24629329
Print-ISSN:: 1931-3128
TUM Institution:: Institut für Virologie
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