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Title:

Comparative analysis of monocyte subsets in the pig.

Document type:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Fairbairn, Lynsey; Kapetanovic, Ronan; Beraldi, Dario; Sester, David P; Tuggle, Chris K; Archibald, Alan L; Hume, David A
Abstract:
Human and mouse monocyte can be divided into two different subpopulations based on surface marker expression: CD14/16 and Ly6C/CX3CR1, respectively. Monocyte subpopulations in the pig were identified based on reciprocal expression of CD14 and the scavenger receptor CD163. The two populations, CD14(hi)-CD163(low) and CD14(low)-CD163(hi), show approximately equal abundance in the steady-state. Culture of pig PBMCs in CSF1 indicates that the two populations are a maturation series controlled by thi...     »
Journal title abbreviation:
J Immunol
Year:
2013
Journal volume:
190
Journal issue:
12
Pages contribution:
6389-96
Language:
eng
Fulltext / DOI:
doi:10.4049/jimmunol.1300365
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/23667115
Print-ISSN:
0022-1767
TUM Institution:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene
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