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Title:

[[11C]choline as a pharmacodynamic marker for docetaxel therapy. Response assessment in a LNCaP prostate cancer xenograft mouse model].

Document type:
English Abstract; Journal Article
Author(s):
Schwarzenböck, S; Sachs, D; Souvatzoglou, M; Schuster, T; Nawroth, R; Weirich, G; Treiber, U; Wester, HJ; Ziegler, S; Schwaiger, M; Senekowitsch-Schmidtke, R; Krause, BJ
Abstract:
The aim of this study was to determine whether [11C]choline can be used for docetaxel therapy response assessment in a LNCaP-prostate cancer xenograft mouse model using [11C]choline small-animal PET/CT. Animals, methods: The androgen-dependent human prostate cancer cell line LNCaP was implanted subcutaneously into the left flanks of 17 SCID-mice, 12.5 mg testosterone platelets were implanted in the neck wrinkle. All mice were injected 4-6 weeks after xenograft implantation with 37 MBq [11C]choli...     »
Journal title abbreviation:
Nuklearmedizin
Year:
2013
Journal volume:
52
Journal issue:
4
Pages contribution:
141-7
Language:
de
Fulltext / DOI:
doi:10.3413/Nukmed-0521-12-07
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/23396481
Print-ISSN:
0029-5566
TUM Institution:
Institut für Allgemeine Pathologie und Pathologische Anatomie; Institut für Medizinische Statistik und Epidemiologie; Klinik und Poliklinik für Nuklearmedizin; Urologische Klinik und Poliklinik
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