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Document type:
Journal Article; Research Support, Non-U.S. Gov't; Article 
Author(s):
Grünewald, Thomas G P; Willier, Semjon; Janik, Dirk; Unland, Rebekka; Reiss, Cora; Prazeres da Costa, Olivia; Buch, Thorsten; Dirksen, Uta; Richter, Günther H S; Neff, Frauke; Burdach, Stefan; Butt, Elke 
Title:
The Zyxin-related protein thyroid receptor interacting protein 6 (TRIP6) is overexpressed in Ewing's sarcoma and promotes migration, invasion and cell growth. 
Abstract:
Ewing's sarcoma (ES) is the second most common bone-associated malignancy in children and is driven by the fusion oncogene EWS/FLI1 and characterised by rapid growth and early metastasis. Here, we explored the role of the Zyxin-related protein thyroid receptor interacting protein 6 (TRIP6) in ES. The Zyxin family comprises seven homologous proteins involved in migration and proliferation of many cell types of which Zyxin has been described as a tumour suppressor in ES.By interrogation of publish...    »
 
Journal title abbreviation:
Biol Cell 
Year:
2013 
Journal volume:
105 
Journal issue:
11 
Pages contribution:
535-47 
Language:
eng 
Fulltext / DOI:
Print-ISSN:
0248-4900 
TUM Institution:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene; Klinik und Poliklinik für Kinderheilkunde und Jugendmedizin