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Document type:
Journal Article; Research Support, Non-U.S. Gov't; Article 
Author(s):
Poos, Kathrin; Smida, Jan; Nathrath, Michaela; Maugg, Doris; Baumhoer, Daniel; Korsching, Eberhard 
Title:
How microRNA and transcription factor co-regulatory networks affect osteosarcoma cell proliferation. 
Abstract:
Osteosarcomas (OS) are complex bone tumors with various genomic alterations. These alterations affect the expression and function of several genes due to drastic changes in the underlying gene regulatory network. However, we know little about critical gene regulators and their functional consequences on the pathogenesis of OS. Therefore, we aimed to determine microRNA and transcription factor (TF) co-regulatory networks in OS cell proliferation. Cell proliferation is an essential part in the pat...    »
 
Journal title abbreviation:
PLoS Comput Biol 
Year:
2013 
Journal volume:
Journal issue:
Pages contribution:
e1003210 
Language:
eng 
Print-ISSN:
1553-734X 
TUM Institution:
Klinik und Poliklinik für Kinderheilkunde und Jugendmedizin