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Titel:

Claudin 18.2 is a target for IMAB362 antibody in pancreatic neoplasms.

Dokumenttyp:
Journal Article
Autor(en):
Wöll, S; Schlitter, AM; Dhaene, K; Roller, M; Esposito, I; Sahin, U; Tureci, O
Abstract:
The majority of pancreatic neoplasms are characterized by a generally lethal progress within a short period of time after primary diagnosis and the mortality of patients is expected to increase further. Due to lack of efficient screening programs and moderate response to treatments, novel compounds for treatment are needed. We investigated the CLDN18.2 expression in affected patients as in vitro feasibility study for a potential treatment with the novel antibody IMAB362. Therefore, we analyzed t...     »
Zeitschriftentitel:
Int J Cancer
Jahr:
2014
Band / Volume:
134
Heft / Issue:
3
Seitenangaben Beitrag:
731-9
Sprache:
eng
Volltext / DOI:
doi:10.1002/ijc.28400
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/23900716
Print-ISSN:
0020-7136
TUM Einrichtung:
Institut für Allgemeine Pathologie und Pathologische Anatomie
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