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Title:

cGMP-dependent protein kinases (cGK).

Document type:
Journal Article; Research Support, Non-U.S. Gov't; Review
Author(s):
Hofmann, Franz; Wegener, Jörg W
Abstract:
cGMP-dependent protein kinases (cGK) are serine/threonine kinases that are widely distributed in eukaryotes. Two genes-prkg1 and prkg2-code for cGKs, namely, cGKI and cGKII. In mammals, two isozymes, cGKI? and cGKI?, are generated from the prkg1 gene. The cGKI isozymes are prominent in all types of smooth muscle, platelets, and specific neuronal areas such as cerebellar Purkinje cells, hippocampal neurons, and the lateral amygdala. The cGKII prevails in the secretory epithelium of the small inte...     »
Journal title abbreviation:
Methods Mol Biol
Year:
2013
Journal volume:
1020
Pages contribution:
17-50
Language:
eng
Fulltext / DOI:
doi:10.1007/978-1-62703-459-3_2
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/23709024
Print-ISSN:
1064-3745
TUM Institution:
Institut für Pharmakologie und Toxikologie
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