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Title:

Survivin and pAkt as potential prognostic markers in squamous cell carcinoma of the head and neck.

Document type:
Journal Article; Article
Author(s):
Pickhard, Anja; Gröber, Simone; Haug, Anna Katharina; Piontek, Guido; Wirth, Markus; Straßen, Ulrich; Rudelius, Martina; Reiter, Rudolf
Abstract:
The purpose of our study was to investigate the expression patterns of cell cycle regulatory proteins and members of the epidermal growth factor receptor (EGFR) signaling pathway in squamous cell carcinoma of the head and neck (HNSCC).The expression levels of survivin, Bub1 B (budding uninhibited by benzimidazoles 1 homolog beta), PLK-1 (polo-like kinase 1), Ki-67, cyclin D1, p53, EGFR, pMAPK (phosphorylated mitogen-activated protein kinase), pAkt (phosphorylated protein kinase B), and PTEN (pho...     »
Journal title abbreviation:
Oral Surg Oral Med Oral Pathol Oral Radiol
Year:
2014
Journal volume:
117
Journal issue:
6
Pages contribution:
733-42
Language:
eng
Fulltext / DOI:
doi:10.1016/j.oooo.2014.02.005
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/24726415
Print-ISSN:
2212-4403
TUM Institution:
Hals-Nasen-Ohrenklinik und Poliklinik
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