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Title:

Magnetic and acoustically active microbubbles loaded with nucleic acids for gene delivery.

Document type:
Journal Article; Research Support, Non-U.S. Gov't; Journal Article
Author(s):
Vlaskou, Dialechti; Plank, Christian; Mykhaylyk, Olga
Abstract:
Targeted gene or drug delivery aims to locally accumulate the active agent and achieve the maximum local therapeutic effect at the target-site while reducing unwanted effects at nontarget sites. A further development of the magnetic drug-targeting concept is combining it with an ultrasound-triggered delivery using magnetic microbubbles as a carrier for gene or drug delivery. For this purpose, selected magnetic nanoparticles (MNPs), phospholipids, and nucleic acid are assembled in the presence of...     »
Journal title abbreviation:
Methods Mol Biol
Year:
2013
Journal volume:
948
Pages contribution:
205-41
Language:
eng
Fulltext / DOI:
doi:10.1007/978-1-62703-140-0_15
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/23070773
Print-ISSN:
1064-3745
TUM Institution:
Institut für Experimentelle Onkologie und Therapieforschung
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