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Titel:

Prefabrication of 3D cartilage contructs: towards a tissue engineered auricle - a model tested in rabbits.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
von Bomhard, Achim; Veit, Johannes; Bermueller, Christian; Rotter, Nicole; Staudenmaier, Rainer; Storck, Katharina; The, Hoang Nguyen
Abstract:
The reconstruction of an auricle for congenital deformity or following trauma remains one of the greatest challenges in reconstructive surgery. Tissue-engineered (TE) three-dimensional (3D) cartilage constructs have proven to be a promising option, but problems remain with regard to cell vitality in large cell constructs. The supply of nutrients and oxygen is limited because cultured cartilage is not vascular integrated due to missing perichondrium. The consequence is necrosis and thus a loss of...     »
Zeitschriftentitel:
PLoS ONE
Jahr:
2013
Band / Volume:
8
Heft / Issue:
8
Seitenangaben Beitrag:
e71667
Sprache:
eng
Volltext / DOI:
doi:10.1371/journal.pone.0071667
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/23951215
Print-ISSN:
1932-6203
TUM Einrichtung:
Hals-Nasen-Ohrenklinik und Poliklinik; Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie
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