Gorrini, Chiara;Baniasadi, Pegah S;Harris, Isaac S;Silvester, Jennifer;Inoue, Satoshi;Snow, Bryan;Joshi, Purna A;Wakeham, Andrew;Molyneux, Sam D;Martin, Bernard;Bouwman, Peter;Cescon, David W;Elia, Andrew J;Winterton-Perks, Zoe;Cruickshank, Jennifer;Brenner, Dirk;Tseng, Alan;Musgrave, Melinda;Berman, Hal K;Khokha, Rama;Jonkers, Jos;Mak, Tak W;Gauthier, Mona L
BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival.
J Exp Med
2013
210
8
1529-44

Garbers, Christoph;Kuck, Fabian;Aparicio-Siegmund, Samadhi;Konzak, Kirstin;Kessenbrock, Mareike;Sommerfeld, Annika;Häussinger, Dieter;Lang, Philipp A;Brenner, Dirk;Mak, Tak W;Rose-John, Stefan;Essmann, Frank;Schulze-Osthoff, Klaus;Piekorz, Roland P;Scheller, Jürgen
Cellular senescence or EGFR signaling induces Interleukin 6 (IL-6) receptor expression controlled by mammalian target of rapamycin (mTOR).
Cell Cycle
2013
12
21
3421-32

Greil, Johann;Rausch, Tobias;Giese, Thomas;Bandapalli, Obul R;Daniel, Volker;Bekeredjian-Ding, Isabelle;Stütz, Adrian M;Drees, Christoph;Roth, Susanne;Ruland, Jürgen;Korbel, Jan O;Kulozik, Andreas E
Whole-exome sequencing links caspase recruitment domain 11 (CARD11) inactivation to severe combined immunodeficiency.
J Allergy Clin Immunol
2013
131
5
1376-83.e3

Jabara, Haifa H;Ohsumi, Toshiro;Chou, Janet;Massaad, Michel J;Benson, Halli;Megarbane, Andre;Chouery, Eliane;Mikhael, Raymond;Gorka, Oliver;Gewies, Andreas;Portales, Pierre;Nakayama, Toshinori;Hosokawa, Hiroyuki;Revy, Patrick;Herrod, Henry;Le Deist, Francoise;Lefranc, Gerard;Ruland, Jürgen;Geha, Raif S
A homozygous mucosa-associated lymphoid tissue 1 (MALT1) mutation in a family with combined immunodeficiency.
J Allergy Clin Immunol
2013
132
1
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del Fresno, Carlos;Soulat, Didier;Roth, Susanne;Blazek, Katrina;Udalova, Irina;Sancho, David;Ruland, Jürgen;Ardavín, Carlos
Interferon-? production via Dectin-1-Syk-IRF5 signaling in dendritic cells is crucial for immunity to C. albicans.
Immunity
2013
38
6
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Thai, To-Ha;Patterson, Heide Christine;Pham, Duc-Hung;Kis-Toth, Katalin;Kaminski, Denise A;Tsokos, George C
Deletion of microRNA-155 reduces autoantibody responses and alleviates lupus-like disease in the Fas(lpr) mouse.
Proc Natl Acad Sci U S A
2013
110
50
20194-9

Wang, Donghai;Höing, Susanne;Patterson, Heide Christine;Ahmad, Umtul M;Rathinam, Vijay A K;Rajewsky, Klaus;Fitzgerald, Katherine A;Golenbock, Douglas T
Inflammation in mice ectopically expressing human Pyogenic Arthritis, Pyoderma Gangrenosum, and Acne (PAPA) Syndrome-associated PSTPIP1 A230T mutant proteins.
J Biol Chem
2013
288
7
4594-601

Neumann, Konstantin;Ruland, Jürgen
Kinases conquer the inflammasomes.
Nat Immunol
2013
14
12
1207-8

Schlauderer, Florian;Lammens, Katja;Nagel, Daniel;Vincendeau, Michelle;Eitelhuber, Andrea C;Verhelst, Steven H L;Kling, Dale;Chrusciel, Al;Ruland, Jürgen;Krappmann, Daniel;Hopfner, Karl-Peter
Structural analysis of phenothiazine derivatives as allosteric inhibitors of the MALT1 paracaspase.
Angew Chem Int Ed Engl
2013
52
39
10384-7

Roth, Susanne;Ruland, Jürgen
Caspase recruitment domain-containing protein 9 signaling in innate immunity and inflammation.
Trends Immunol
2013
34
6
243-50