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Title:

The impact of breed and tissue compartment on the response of pig macrophages to lipopolysaccharide.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Kapetanovic, Ronan; Fairbairn, Lynsey; Downing, Alison; Beraldi, Dario; Sester, David P; Freeman, Tom C; Tuggle, Christopher K; Archibald, Alan L; Hume, David A
Abstract:
The draft genome of the domestic pig (Sus scrofa) has recently been published permitting refined analysis of the transcriptome. Pig breeds have been reported to differ in their resistance to infectious disease. In this study we examine whether there are corresponding differences in gene expression in innate immune cellsWe demonstrate that macrophages can be harvested from three different compartments of the pig (lungs, blood and bone-marrow), cryopreserved and subsequently recovered and differen...     »
Journal title abbreviation:
BMC Genomics
Year:
2013
Journal volume:
14
Pages contribution:
581
Language:
eng
Fulltext / DOI:
doi:10.1186/1471-2164-14-581
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/23984833
TUM Institution:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene
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