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Title:

Role of transmembrane domains of hepatitis B virus small surface proteins in subviral-particle biogenesis.

Document type:
Journal Article; Journal Article
Author(s):
Siegler, VD; Bruss, V
Abstract:
The hepatitis B virus (HBV) surface proteins not only are incorporated into the virion envelope but in addition form subviral particles (SVP) consisting solely of surface proteins and lipids. Heterologous expression of the small HBV envelope protein S produces secreted spherical SVP 20 nm in diameter, with approximately 100 S molecules per particle. The pathway leading from the initial S translation product as a multispanning transmembrane protein to the final SVP is largely unknown. To investig...     »
Journal title abbreviation:
J Virol
Year:
2013
Journal volume:
87
Journal issue:
3
Pages contribution:
1491-6
Language:
eng
Fulltext / DOI:
doi:10.1128/JVI.02500-12
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/23152523
Print-ISSN:
0022-538X
TUM Institution:
Institut für Virologie
 BibTeX