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Titel:

Role of transmembrane domains of hepatitis B virus small surface proteins in subviral-particle biogenesis.

Dokumenttyp:
Journal Article; Journal Article
Autor(en):
Siegler, VD; Bruss, V
Abstract:
The hepatitis B virus (HBV) surface proteins not only are incorporated into the virion envelope but in addition form subviral particles (SVP) consisting solely of surface proteins and lipids. Heterologous expression of the small HBV envelope protein S produces secreted spherical SVP 20 nm in diameter, with approximately 100 S molecules per particle. The pathway leading from the initial S translation product as a multispanning transmembrane protein to the final SVP is largely unknown. To investig...     »
Zeitschriftentitel:
J Virol
Jahr:
2013
Band / Volume:
87
Heft / Issue:
3
Seitenangaben Beitrag:
1491-6
Sprache:
eng
Volltext / DOI:
doi:10.1128/JVI.02500-12
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/23152523
Print-ISSN:
0022-538X
TUM Einrichtung:
Institut für Virologie
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