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Titel:

Mechanisms of peripheral tolerance to allergens.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Review
Autor(en):
Soyer, OU; Akdis, M; Ring, J; Behrendt, H; Crameri, R; Lauener, R; Akdis, CA
Abstract:
The immune system is regulated to protect the host from exaggerated stimulatory signals establishing a state of tolerance in healthy individuals. The disequilibrium in immune regulatory vs effector mechanisms results in allergic or autoimmune disorders in genetically predisposed subjects under certain environmental conditions. As demonstrated in allergen-specific immunotherapy and in the healthy immune response to high-dose allergen exposure models in humans, T regulatory cells are essential in...     »
Zeitschriftentitel:
Allergy
Jahr:
2013
Band / Volume:
68
Heft / Issue:
2
Seitenangaben Beitrag:
161-70
Sprache:
eng
Volltext / DOI:
doi:10.1111/all.12085
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/23253293
Print-ISSN:
0105-4538
TUM Einrichtung:
Klinik und Poliklinik für Dermatologie und Allergologie; Molekulare Allergologie (Prof. Schmidt-Weber)
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