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Titel:

ISL1 expression is not restricted to pancreatic well-differentiated neuroendocrine neoplasms, but is also commonly found in well and poorly differentiated neuroendocrine neoplasms of extrapancreatic origin.

Dokumenttyp:
Journal Article; Article
Autor(en):
Agaimy, A; Erlenbach-Wünsch, K; Konukiewitz, B; Schmitt, AM; Rieker, RJ; Vieth, M; Kiesewetter, F; Hartmann, A; Zamboni, G; Perren, A; Klöppel, G
Abstract:
The human insulin gene enhancer-binding protein islet-1 (ISL1) is a transcription factor involved in the differentiation of the neuroendocrine pancreatic cells. Recent studies identified ISL1 as a marker for pancreatic well-differentiated neuroendocrine neoplasms. However, little is known about ISL1 expression in pancreatic poorly differentiated and in extrapancreatic well and poorly differentiated neuroendocrine neoplasms. We studied the immunohistochemical expression of ISL1 in 124 neuroendocr...     »
Zeitschriftentitel:
Mod Pathol
Jahr:
2013
Band / Volume:
26
Heft / Issue:
7
Seitenangaben Beitrag:
995-1003
Sprache:
eng
Volltext / DOI:
doi:10.1038/modpathol.2013.40
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/23503646
Print-ISSN:
0893-3952
TUM Einrichtung:
Institut für Allgemeine Pathologie und Pathologische Anatomie
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