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Title:

Chemokine-driven lymphocyte infiltration: an early intratumoural event determining long-term survival in resectable hepatocellular carcinoma.

Document type:
Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
Author(s):
Chew, V; Chen, J; Lee, D; Loh, E; Lee, J; Lim, KH; Weber, A; Slankamenac, K; Poon, RT; Yang, H; Ooi, LL; Toh, HC; Heikenwalder, M; Ng, IO; Nardin, A; Abastado, JP
Abstract:
Hepatocellular carcinoma (HCC) is a heterogeneous disease with poor prognosis and limited methods for predicting patient survival. The nature of the immune cells that infiltrate tumours is known to impact clinical outcome. However, the molecular events that regulate this infiltration require further understanding. Here the ability of immune genes expressed in the tumour microenvironment to predict disease progression was investigated.Using quantitative PCR, the expression of 14 immune genes in r...     »
Journal title abbreviation:
Gut
Year:
2012
Journal volume:
61
Journal issue:
3
Pages contribution:
427-38
Language:
eng
Fulltext / DOI:
doi:10.1136/gutjnl-2011-300509
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/21930732
Print-ISSN:
0017-5749
TUM Institution:
Institut für Virologie
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